李沁雨

职称职务：讲师

学科专业：微生物学、合成生物学

研究方向：工业微生物、酶工程

电子邮箱：1090090@hnust.edu.cn

学习经历

2013年-2017年，湖南大学生物学院，生物技术专业，获理学学士学位

2017年-2023年，上海科技大学与中国科学院上海高等研究院联合培养，生物学专业，硕博连读，获理学博士学位

工作经历

2023年-至今 湖南科技大学 生命科学与健康学院，讲师

主要研究领域与兴趣

微生物的筛选鉴定、发酵与代谢调控研究

微生物基因编辑系统的开发与应用

工业酶的开发与定向进化

代表性成果

[1] Li, Q., Chen, X., Wu, Y., Chen, Z., Han, Y., Zhou, P., Shi, J.* & Zhao, Z.* A Study of Type II ɛ-PL Degrading Enzyme (pldII) in Streptomyces albulus through the CRISPRi System. Int. J. Mol. Sci, 2022, 23(12).

[2] Wang, C^#., Li, Q.^#, Zhou, P., Chen, X., Shi, J., Zhao, Z.* Bioprocess Engineering, Transcriptome, and Intermediate Metabolite Analysis of L-serine High-yielding Escherichia coli W3110. Microorganisms, 2022, 10(10).

[3] Li, Q., Chen, X., Liu, X., Chen, Z., Han, Y., Zhou, P., Shi, J.* & Zhao, Z.* PTCL1-EstA from Paenarthrobacter aurescens TC1, a Candidate for Industrial Application Belonging to the VIII Esterase Family. Catalysts, 2022, 12(5).

[4] Chen, Z., Li, Q., Zhou, P., Zhao, Z., Li, B.* Analysis of Key Metabolic Pathways for L-serine Synthesis in Escherichia coli Based on Transcriptome Sequencing in Different Carbon Sources. BIOCHEM ENG J, 2023, 191(10).

[5] Chen, Z., Chen, X., Li, Q., Zhou, P., Shi, J.* & Zhao, Z.* Transcriptome analysis reveals potential mechanisms of L-serine production by Escherichia coli fermentation in different carbon-nitrogen ratio medium. Foods, 2022, 11(14).

[6] Chen, X., Wu, C., Li, Q., Zhou, P., Chen, Z., Han, Y., Shi, J.* & Zhao, Z.* Effect of thermophilic microbial agents on antibiotic resistance genes and microbial communities during co-composting of pig manure and tea stalks. Sustainability, 2022, 14(19).

[7] Chen, X., Wu, C., Wang, C., Li, Q., Zhou, P., Wei, D., Shi, J., Zhao, Z.* Effect of Geobacillus toebii GT-02 addition on composition transformations and microbial community during thermophilic fermentation of bean dregs. Scientific Reports, 19949 (2021).

[8] Chen, X., Du, G, Wu, C., Li, Q., Zhou, P., Shi, J., Zhao, Z.* Effect of thermophilic microbial agents on nitrogen transformation, nitrogen functional genes, and bacterial communities during bean dregs composting. Environmental Science and Pollution Research, 2022: 1-15.